A 60-year-old woman presents with generalized edema, skin ulceration and hypeension. Urine examination shows subnephrotic proteinuria

A. Post-streptococcal Glomerulonephritis

B. Essential Mixed Cryoglobulinemia

C. Membranoproliferative Glomerulonephritis (MPGN)

D. Focal SegmentalGlomerulosclerosis (FSGS)

Correct Answer: Essential Mixed Cryoglobulinemia

Description: Answer is B > C (Essential mixed cryoglobulinemia): The presence of skin ulceration on clinical examination in a female patient around the 6th decade ors a diagnosis of Essential Mixed Cryoglobulinemia over MPGN. Neveheless if Essential Mixed Cryoglobulinemia were not amongst the options MPGN would be the single best answer of choice. Membranoproliferative glomerulonephritis is a responsible for 80% of all renal lesions in essential mixed cryoglobulinemia.

Category: Medicine

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