Increased IgA deposits are seen in –

Correct Answer: Henoch Schonlein Purpura
Description: Henoch schonlein purpura This syndrome consists of Pruritic skin lesions characteristically involving the extensor surfaces of arms and legs as well as buttocks. Abdominal manifestations → Pain, vomiting, bleeding Nonnzigratory arthralgia Renal abnormalities The disease most commonly affects children between 3 to 8 years. Renal manifestations Gross or microscopic hematuria Proteinuria Nephrotic syndrome There is deposition of IgA, sometimes with IgG and C3, in the mesangial region. IgA is deposited in the glomerular mesangium in a distribution similar to that of IgA nephropathy. This has led to the concept that IgA nephropathy and Henoch-Schonlein purpura are spectra of the same disease.
Category: Pathology
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