The conjugation of bilirubin to glucuronic acid in the liver –
Correct Answer: Converts a hydrophobic compound to a hydrophilic one
Description: Unconjugated bilirubin (hydrophobic) is converted to conjugated bilirubin (hydrophilic) by the process of conjugation with UDP-glucuronic acid in the liver.
As conjugated bilirubin is hydrophilic (not lipophilic) it cannot cross the plasma membrane easily (lipophilic or lipid soluble substances cross plasma membrane easily). Thus, unconjugated bilirubin (lipophilic) can cross plasma membrane easily but not conjugated bilirubin (hydrophilic).
In neonatal jaundice, conjugation process is immature.
Category:
Biochemistry
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now