The basis of combining Ritonavir with Lopinavir
Correct Answer: CYP3A4 inhibiton NY Ritonavir
Description: Refer Katzung 10/e p810 Ritonavir is a microsomal enzyme inhibitor paicularly of CYP3A4 .it decreases the metabolism of other drugs and thus lower dose of Lopinavir can be used in treatment of HIV when combined with Ritonavir
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