E- cadherin mutation is seen in which type of carcinoma:
Correct Answer: Lobular carcinoma
Description: Loss of E cadherin can contribute to malignant phenotype by allowing easy disintegration of cell which can then invade locally and metastasize. Reduced cell surface expression of E cadherin has been noted in many carcinomas : Stomach carcinoma Breast carcinoma Prostate carcinoma Ovarian carcinoma
Category:
Pathology
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