Major neurotransmitter in afferents in nucleus tractus solitarius to regulate cardiovascular system –
Correct Answer: Glutamate
Description: Ans. is 'b' i.e., Glutamate o Nucleus tractus solitarius (NTS) lies in medulla.o It receives following afferents :-General visceral afferentsFrom tonsil, pharynx, posterior part of tongue, carotid body and sinus - through glossopharyngeal nerve:From pharynx, larynx, trachea, esophagus, and other thoracic and abdominal viscera -through vagus nerve.Special visceral afferentsFrom anterior 2/3 of tongue (except circumvallate papillae) and palate - through facial nerveFrom posterior 1/3 of tongue (including circumvallate papillae) - through glossopharyngeal nerve.From posterior most part of tongue and epiglottis - through vagus nerve.o NTS is involved in regulation of cardiovascular system through baroreceptors and chemoreceptors.o There is a general consensus that glutamate is the neurotransmitter released at the therminals of baroreceptor and chemoreceptor afferents in NTS. -- www.springer.como However, cholinergic, GABAergic, and opioidergic mechanisms are also present in NTS.
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