A drug that binds to a receptor at a site distinct from the active site and alters the affinity of the receptor for the endogenous ligand is a:-
Correct Answer: Allosteric modulator
Description: * Allosteric modulator that binds to a receptor at a site distinct from the active site and alters the affinity of the receptor for the endogenous ligand. * Competitive antagonist binds to the same site as that of agonist, produces surmountable effect i.e. effect of antagonist can be overcome by increasing concentration of agonist. * Inverse agonist and paial agonist also bind to the same site as that of the agonist.
Category:
Pharmacology
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