Most common fibroid associated with malignancy is :
Correct Answer: Intramural
Description: Ans. is b i.e. Intramural Well friends, we will have to rely on logic and the little text available in Shaw Gynae for this answer. I have searched in all books including Novak's Gynecology and Devita - Tumours but without any success. Only Shaw's throws some light on this issue. "Intramural and submucous tumours have a higher potential for Sarcomatous change than Subserous tumour." ... Shaw 14/e. p 319 Since percentage of intramural tumours is much higher than submucous, so we take Intramural as the correct option. But finally it is upto you to decide. Also know : Sarcomatous change is seen in only 0.2 - 0.5% of cases. The malignant process begins from the centre.deg Diagnosis is made by histological examination of the removed myoma.deg Changes seen in Myoma are : - Sarcomatous Myoma is yellowish grey in colour (Normally pinkish white), with soft and friable consistency (Instead of firm consistency). Non encapsulation of the tumour. (Normally fibroid is surrounded by a pseudo capsule made of connective tissue). Sarcomas with malignant behavior have 10 or more Mitosis per high power field. becomes painful, tender, grows rapidly and produces systematic upset and pyrexia.
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Gynaecology & Obstetrics
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