Solubility of cholesterol depends on:

Correct Answer: Bile salts
Description: Ans: C (Bile salts) Ref: Harper's illustrated biochemistry,28th edition & Ganong's Physiology & Bandyopadhyay A et al. Cholesterol solubility by bile salts in pure and mixed states. J Phys Chem: 1991: 95: 4529-34Explanation:"Bile salts are metabolic products which together with phospholipids solubilize cholesterol forming bileCholesterol is only slightly soluble in water; it can dissolve and travel in the water-based bloodstream at exceedingly small concentrations.Since cholesterol is insoluble in blood, it is transported in the circulatory system within lipoproteins, complex discoidai particles that have an exterior composed of amphiphilic proteins and lipids whose outward-facing surfaces are water-soluble and inward-facing surfaces are lipid-soluble; triglycerides and cholesterol esters are carried internally.Phospholipids and cholesterol, being amphipa- thic. are transported in the surface monolayer of the lipoprotein particle.
Category: Biochemistry
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