All of the following are true about Herpes group virus except:
Correct Answer: Burkitt’s lymphoma involves T-cells
Description: Burkitt’s lymphoma = ALL L3.
Burkitt leukemia/lymphoma is now considered a mature B-cell neoplasm.
It was formerly classified as precursor B ALL(Acute lymphoblastic leukemia) with L3 morphology (FAB-L3).
The lymphoma cells are positive for B cell antigens, express surface immunoglobulins, and lack TdT expression with nearly 100% of cells being positive for ki-67.
Feature of Herpes Virus:
Enveloped Ds DNA virus, nucleocapsid is icosahedral.
Are enveloped, so are susceptible to fat solvent like ether, alcohol, bile salts.
Replicate in nucleus, forming cowdry type A intranuclear (lipschutz) inclusion bodies.
Some herpes virus have been implicated with malignancies.
EBV: Nasopharyngeal carcinoma
HSV - 2 - Carcinoma cervix
HHV-8 - Kaposi sarcoma, Multiple myeloma.
Category:
Microbiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now