Which of the following liver enzymes is predominantly mitochondrial
Correct Answer: SGOT (AST)
Description: Liver enzymes location
Ectoenzymes (Plasma membrane-bound) :- 5' nucleotidase (also called nucleotide phosphatase, NTP), Gamma-glutamyl transferase (gamma-glutamyl transpeptidase : GGT), alkaline phosphatase (ALP).
Mitochondrial:- Glutamate dehydrogenase (GDH), Aspartate aminotransferase (AST) or SGOT mitochondrial isoenzyme.
Cytosolic:- Lactate dehydrogenase (LDH), Alanine transaminase (ALT) or SGPT, SGOT (AST) cytosolic isoenzyme.
Note:- In liver, the predominant isoenzyme of SGOT (AST) is mitochondrial.
Category:
Biochemistry
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