Mutation not seen in diffuse type of gastric cancer?
Correct Answer: APC
Description: Hereditary diffuse gastric cancer is an inherited form of gastric cancer. Patients with this disorder, resulting from a gene mutation for the cell adhesion molecule E-cadherin, have an 80% lifetime incidence of developing gastric cancer. Inactivation of the tumor suppressor genes p53 and p16 has been repoed in diffuse and intestinal-type cancers. Adenomatous polyposis coli gene mutations tend to be more frequent in intestinal-type gastric cancers. Sabiston 20e pg: 1240.
Category:
Surgery
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now