Which of the following least likely to cause increase in bradykinin production?
Correct Answer: Irbesaan
Description: Ans 'c' i.e. Irbesaan AT-II antagonists (e.g. lrbesaan) do not inhibit ACE (rather they block AT-II receptor). o Therefore, they do not interfere with degradation of bradykinin and substance P (bradykinin and substance P are degraded by ACE). o For the same reason AT-II antagonists do not cause cough & angiodema (caused by ACE inhibitors)
Category:
Pharmacology
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