Hormone that stimulates gluconeogenesis is:
Correct Answer: Both of the above
Description: Ans:D.)Both of the Above. Glucagon and epinephrine, hormones that are responsive to a decrease in blood glucose, inhibit glycolysis and stimulate gluconeogenesis in the liver by increasing the concentration of cAMP. This in turn activates cAMP-dependent protein kinase, leading to the phosphorylation and inactivation of pyruvate kinase. They also affect the concentration of fructose 2,6-bisphosphate and therefore glycolysis and gluconeogenesis Ref: Harper 28thedition, chapter 20.
Category:
Biochemistry
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