Wof agent is used to prevent hemorrhagic cystitis caused by cyclophosphamide and ifosfamide
Correct Answer: Mesna
Description: To prevent hemorrhagic cystitis mesna is routinely given with the drugs. Mesna is a -SH compound that is excreted in urine--binds and inactivates the vasicotoxic metabolites(Acrolein) of ifosfamide and cyclophosphamide. Ref:- kd tripathi; pg num:-860
Category:
Pharmacology
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