Synthesis of which of the following clotting factors is not affected in liver disease?
Correct Answer: Factor VIII
Description: Liver synthesizes all coagulation factors except factor VIII and vWF which are produced by endothelial cells. So production of factor VIII is not affected in liver disease. Clotting factors produced by the liver are factors I, II, V, VII, IX and X. Liver also synthesizes activators and inhibitors of the fibrinolytic system. It is also involved in the synthesis, catabolism and clearence of both procoagulants and anticoagulants such as antithrombin III, fibrin degradation products and plasminogen activators. Ref: The Surgical Review: An Integrated Basic And Clinical Science Study Guide By Pavan Atluri, Page 300
Category:
Physiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now