True about amoebic colitis is –
Correct Answer: Caused by E histolytica
Description: Hepatic involvement is the most common extraintestinal complication of amoebiasis caused by entamoeba histolytica. Though trophozoites reach the liver in most cases of amoebic dysenterys, only in a small propoion do they manage to lodge and multiply there. Several patients with amoebic colitis develop an enlarged tender liver without detectable impairment of liver function or fever ENTAMOEBA COLI It is a nonpathogenic commensal intestinal amoeba. Its medical impoance is that it has to be differentiated from E.histolytica. It is larger, about 20 to 50 mm with sluggish motility and contains ingested bacteria but not red cells. The nucleus is clearly visible in unstained films and has a large eccentric karyosome and thick nuclear membrane lined with coarse granules of chromatin. Cysts are large, 10 to 30 mm in size, with a prominent glycogen mass in the early stage. The chromatoid bodies are splinter like and irregular. The mature cyst has eight nuclei. The life cycle is the same as in E.histolytica except that it remains a luminal commensal without tissue invasion and is nonpathogenic. TEXTBOOK OF MEDICAL PARASITOLOGY,CKJ PANIKER,6TH EDITION,PAGE NO30
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