Sildenafil, a gra like medicine, can be used for which of the following conditions?
Correct Answer: Pulmonary hypeension
Description: Phosphodiesterase inhibitors like sildenafil are indicated in Erectile dysfunction (Drug of choice) and Pulmonary hypeension Sildenafil selectively inhibits Phosphodiesterase (PDE)-V leading to increased cGMP levels and so is useful in erectile dysfunction. It can be administered orally. Adverse effects include headache, nasal congestion, flushing, visual disturbances (blue vision) etc. Colour vision defect is due to inhibition of PDE-VI present in the retina. Apa from their use in ED, sildenafil can also be used in the management of pulmonary hypeension. Other drugs of this group are vardenafil, udenafil, avanafil and tadalafil. Tadalafil- PDE-6 inhibition is not present
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now