10 years old Ramu has increasing muscle weakness and raised CPK levels. The most likely defect is in plasma membrane of-
Correct Answer: Muscle fibres
Description: Ans. is 'b' Muscle fibres (Ref. Chandrasoma Taylor, 3/e, p. 953).Increase in CPK level with muscle weakness suggests muscle cell damage.Creatine kinase is an enzyme found mainly in:Skeletal muscle*Heart*Brain*Its levels will be raised in the serum when any of the above mentioned cell is damaged.There are various isotypes of the enzyme which are specific for difference cells.Enzyme - TissueCreatine kinase - Heart*(MB isoenzyme)Creatine kinase - Brain*(BB isoenzyme)Creatine kinase - Skeletal muscle*(MM isoenzyme)Other enzymes elevated in muscle diseasesAldolase*Aminotransferases specially (ACT) *Lactate dehydrogenase*
Category:
Pediatrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now