28 year old male met with an accident and sustained severe crush injury. He is most likely develop –
Correct Answer: Acute renal failure
Description: Severe crush injury results in rhabdomyolysis(breakdown of muscle tissue -myoglobin is released into blood, damaging the kidneys. ) Other causes of rhabdomyolysis Muscle ischemia Immobilisation Prolonged seizure activity Excessive exercise ,heat stroke or malignant hypehermia,myopathies,infections Metabolic disorders (severe hypothyroidism, hypophosphatemia) Ref:HARRISON 20 th edition pg no. 2103
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