True about pKa is:-

Correct Answer: pH at which ionized fraction of drug equals to unionized fraction
Description: * pKa is the pH at which ionized fraction(50%) of drug equals to unionized fraction(50%). * i.e. 50% is lipid soluble and 50% is water soluble. * It is the pH at which 50% of drug can cross the membrane and 50% of drug cannot cross the membrane.
Category: Pharmacology
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