The following feature is common to both cytotoxic T – cells and NK cells –
Correct Answer: Effective against virus infected cells
Description: Ans. is 'c' i.e., Effective against virus infected cells Natural killer cells o are first line of defense against virus laden cells and neoplastic cells o cytotoxity is not MHC restricted Cytotoxic T cells o they are antigen specific T cells whose function is to produce antigen specific lysis of target cells by direct cell-to-cell contact. o are usually CD, + class I MHC restricted T cells. o are impoant in defense against viral infections of tissues. Thus the feature common to both cytotoxic T-cells and NK cells is effectivity against virus infected cells. Cytotoxicity of different cells o Natural killar cells o Cytotoxic T-cells o Antibody dependent cytotoxic T-cells (ADCC) (a type of null cell) Not antibody dependent Not MHC restricted Class I MHC restricted Not antibody dependent Antibody dependent Not MHC restricted
Category:
Pathology
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