All of the following factors tend to increase the volume of distrubtion of a drug except
Correct Answer: High plasma protein binding
Description: Ref-katzung 10/e per,35 If a drug is highly bound to plasma proteins ,it is more likely to stay in blood.thus it's Vd will be less . Low ionization ours the distribution of a drug because unionized molecules can cross the membrane of blood vessels and the tissue More lipid soluble drugs can easily cross the membrane and are more likely to be highly distributed
Category:
Anatomy
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now