Central obesity is seen in;
Correct Answer: Cushing's disease
Description: Among given options Central obesity is seen in Cushing's disease. CUSHING'S DISEASE: Form of Cushing's syndrome in which pituitary gland releases too much of ACTH Features of Cushing's syndrome: Moon facies Centripetal Obesity Proximal myopathy Violet/ purple Striae, Thin skin, Purpura Buffalo hump Weight gain / Lemon on sticks description | Peripheral resistance - HTN Insulin resistance - sugar FBS > 126 mg%; 2hr > 200 mg% Coisol | - Activates ENaC - causes salt & water retention; Hypokalemic alkalosis Coisol | - Activates Sex steroid receptors Female - Hirsutism, weight gain, oligomenorrhea, infeility Hyperpigmentation: (+-)
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