Characteristic pathological finding in carcinoid of hea-
Correct Answer: Fibrous endocordial thickening of right ventricle andtricuspid valve
Description: The carcinoid syndrome results from bioactive compounds such as serotonin released by carcinoid tumors (; systemic manifestations include flushing, diarrhea, dermatitis, and bronchoconstriction. Carcinoid hea disease refers to the cardiac manifestation caused by the bioactive systemic syndrome develops. Cardiac lesions typically do not occur until there is a massive hepatic metastatic burden, since the liver normally catabolizes circulating mediators before they can affect the hea. Classically, endocardium and valves of the right hea are primarily affected since they are the first cardiac tissues bathed by the mediators released by gastrointestinal carcinoid tumors. (Robbins basic pathology,9th edition,pg no.395)
Category:
Pathology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now