A 50-year-old HIV-positive male comes to OPD wit complaints of fever and breathlessness . He is diagnosed as a case of Pneumocystis jiroveci pneumonia (PCP). At what CD4 T cell % ,primary prophylaxis for this condition is recommended to be staed?
Correct Answer: < 20%
Description: NIH/CDC/IDSA Guidelines for the Prevention of Oppounistic Infections in Persons Infected with HIV PATHOGEN INDICATIONS FIRST CHOICE(S) ALTERNATIVES Pneumocystis jirovecii CD4+ T cell count <200/mL or Oropharyngeal candidiasis or Prior bout of PCP Trimethoprim-sulfamethoxazole (TMP-SMX), 1 DS tablet qd PO or TMP-SMX, 1 SS tablet qd PO Dapsone 50 mg bid PO or 100 mg/d POor Dapsone 50 mg/d PO +Pyrimethamine 50 mg/week PO + Leucovorin 25 mg/week PO or (Dapsone 200 mg PO +Pyrimethamine 75 mg PO +Leucovorin 25 mg weekly PO) or Aerosolized pentamidine, 300 mg Respirgard II nebulizer every monthor Atovaquone 1500 mg/d POor TMP-SMX 1 DS tablet 3x/week PO May stop prophylaxis if CD4+ T cell count >200/mL for >=3 months
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