All of the following statements about mycophenolate mofetil are true except :
Correct Answer: It is highly nephrotoxic
Description: Mycophenolate mofetil is a prodrug, its active metabolite is mycophenolic acid.
It is used as an immunosuppressant drug in solid organ transplant patients for refractory rejection and as an alternative to cyclosporine /tacrolimus in patients who do not tolerate these drugs.
- Major toxicity is gastrointestinal (nausea, vomiting, diarrhea, abdominal pain). It can also cause hypertension and reversible neutropenia.
- Unlike cyclosporine and tacrolimus, it does not cause nephrotoxicity.
Category:
Pharmacology
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