Shigella associated hemolytic uramic syndrome is associated with all of the following except?
Correct Answer: Hyperkalemia
Description: Answer is A or None (Hyperkalemia or None) Hyperkalemia is the single best answer of exclusion. HUS may occur with Shigella Dysentriae type I. Clinical features in HUS due to shigella as mentioned in (Harrison 14th/959) include : Oliguria progressing to anuria and renal.failuree Drop in hematocrit progressing to severe anemia and CHFQ CNS abnormalities include - encephalopathic symptoms - seizures - altered consciousness - bizzare posturing * Laboratory : - Profound hyponatremia Q and severe hypoglycemiadeg may be seen - Leukamoid reactions with increased leucocyte counts Qmay be seen - ThrombocytopeniaQ is common cla - Although one might argue that hyperkalemia may as well be a feature of HUS on account of renal failure, 1 have excluded it because all other options have been mentioned directly in the standard Harrison text.
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