Mark the false statement among given options related to heme :
Correct Answer: Heme oxygenase produces CO2 , Fe3+ & water
Description: Synthesis of heme:* In first step of heme synthesis, Glycine amino acid is required* Glycine condenses with succinyl CoA to form 6-amino levulinate which serves as a precursor for heme synthesis. Heme oxygenase uses oxygen & it produces CO, Fe3+ & water. But it does not produce CO2. Copper is necessary for the synthesis of haemoglobin because Cu is a constituent of ALA synthase, needed for heme synthesis. Pyridoxal phosphate is required for the synthesis of d-amino levulinic acid, the precursor for heme. Extra Information Senescent RBCs are destroyed in reticuloendothelial System (RES) releasing hemoglobin Globin pa enters the amino acid pool Heme iron is usually oxidised to ferric iron forming hemin Hemin is the substrate of microsomal Heme Oxygenase system.
Category:
Biochemistry
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