Spongiosis involves-
Correct Answer: Stratum spinosum
Description: Spongiosis is seen in intracellular ( in between keratinocytes ) edema. This results in loss of cohesion between epidermal cells which remain on contact with each other only at desmosomes and so acquire a stellate appearance giving the epidermis a sponge like appearance. Ref: Harrison20th edition pg 1208
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