Which of the following statements is true regarding peussis ?

A. Neurological complication rate of DPT is I in 50000

B. Vaccine efficacy is more than 95%

C. Erythromycin prevents spread of disease between children

D. The degree of polymorphonuclear Leukocytosis correlates with the severity of cough

Correct Answer: Erythromycin prevents spread of disease between children

Description: Ans. is 'c' i.e., Erythromycin prevents spread of disease between children o Efficacy of Peusis Vaccine - repoed to be from 70-90% o Risk of acute encephalopathy - is 1 in 40, 000 cases following DTP vaccine. o Peusis toxin produces Lymphocytosis & not polymorphonuclear Leukoctyosis. Leukocytosis due to absolute lymphocytosis is characteristic in late catarrhal or paraoxysmal stage. o Prophylactic erythromycin prevents infecting bacteria to become established - prevents spread of disease - Park

Category: Social & Preventive Medicine

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