A 42 year old male after being influenced by online weight losing program decides to do an intense workout at gym. But he noticed that even after 45 minutes of workout he didn’t sweat. After that he went for steam bath and then also there was no perspiration. He noticed this from last few days and repoed to Medicine opd for the same . what could be the possible cause for this ?
Correct Answer: Sudomotor failure
Description: Sudomotor Function:- Lack of sweating(perspiration) in above case is suggestive of sudomotor failure Sweating is induced by release of ACh from sympathetic postganglionic fibers. The quantitative sudomotor axon reflex test (QSA) is a measure of regional autonomic function mediated by ACh-induced sweating. The thermoregulatory sweat test (TST) is a qualitative measure of global sweat production in response to an elevation of body temperature under controlled conditions. =Postganglionic lesion:- Both QSA and TST show absent sweating =Preganglionic lesion:- QSA is normal but TST shows anhidrosis. Acquired idiopathic generalized anhidrosis (AIGA) It is a rare disorder having decreased or absent sweating without involvement of autonomic and somatic nervous system and without any longstanding organic cutaneous lesions
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