Which of the following drugs is not used in treatment of bird flu?
Correct Answer: Ribavirin
Description: Ans. b. Ribavirin (Ref: Harrison 19/ep1214; Goodman Gilman 12/ep1609, 1615; Katzung 12/ep886, 887; KDT 7/e p798, 804, 6/e p777)Oral ribavirin is used for chronic HCV infection, not the bird flu."Oral ribavirin in combination with injected pegIFN alfa-2A or -2B has become standard treatment for chronic HCV infection, "-- Goodman Gilman 12/e p1615"Ribavirin is a nucleoside analogue with activity against influenza A and B viruses in vitro. Its efficacy against influenza when administered as an aerosol is reportedly variable, and it is ineffective when administered orally. Its efficacy in the treatment of influenza A or B has not been established. "-- Harrison 19/e p1214"Ribavirin is used primarily to treat hepatitis C, viral hemorrhagic fevers and RSV.""The neuraminidase inhibitor peramivir, a cyclopentane analog, has activity against both influenza A and B viruses. Peramivir received temporary emergency use authorization by FDA for intravenous administration in November 2009 due to the HINI pandemic. "-- Katzung 12/e p887Specific Antiviral Therapy for influenzaNeuraminidase inhibitors zanamivir, oseltamivir & peramivir are used for both influenza A & BQAmantadine & rimantadine are used for influenza AQOseltamivir* DOC for bird flu (H5N1)Q* Treatment of uncomplicated influenza A or B in healthy adults.Zanamivir* Administered by inhalational routeQ* Treatment of uncomplicated influenza A or B in healthy adultsQ.Peramivir* Administered IVQ* Activity against both influenza A & B virusesQLaninamivir* Long acting neuraminidase inhibitorQ* Effective against oseltamivir resistant virusQAmantadine* Active against influenza A onlyQRimantadine* Longer acting than Amantadine, active against influenza A onlyQDrug of Choice in Viral DiseasesDiseaseDrug of Choice* Viral hemorrhagic fever (Lass virus, Rift valley fever, Congo Crimean hemorrhagic fever. Hanta virus)* Respiratory syncytial virus (in high risk patients)* MeaslesRibavirinQ* Seasonal influenza* Avian influenza (bird flu)OseltamivirQ* Oseltamivir resistant influenzaZanamivirQ* Prion diseaseFlupirtineQ* Herpes simplex* VaricellaAcyclovirQ* Acute herpes zosterValacyclovirQ* Cytomegalovirus retinitisGancicyclovirQ
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now