Best specimen for rabies diagnosis in living person:

Correct Answer: Biopsy of hair follicle of neck
Description: o Biopsy of hair follicle of base of neck is more sensitive and considered as the best sample for direct florescent antibody (DFA) test done for antemoem diagnosis of Rabies. o Corneal smears, biopsy from hair follicle from the nape of the neck, and saliva are the used specimens for antemoem diagnosis of rabies. o Corneal impression smear is only 30% sensitive, mainly it is positive in late stage. o The brain biopsy of the dead animal is the specimen of choice for postmoem diagnosis of rabies.
Category: Microbiology
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