Genetic expression of Na KATPAse inducible by-
Correct Answer: Aldosterone
Description: Ans. is 'a' i.e.. Aldosterone Mineralocorticoid actionso The principal mineralocorticoid secreted by adrenal cortex is aldosterone.o The main action of aldosterone is to enhance Na+ reabsorption in the distal convoluted tubule in kidney.o There is an associated increase in K+ and H+ excretion.Excess mineralocorticoid - Na+ and water retention (Hypertension & edema), Hypokalemia, Alkalosis.Mineralocorticoid deficiency (Addison's disease) - Hyperkalemia. Acidosis, Hypotension,o Mechanism of actionMineralocorticoid acts on cytoplasmic receptors.It increases transcription of m.RNA in renal tubular cells to symthesis Aldosterone - induced protein (ATP) which is Na+ K+ ATPase.Symthesis of b-subunit of amiloride sensitive Na+ channel is also induced.
Category:
Physiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now