b-hydroxybutyric aciduria is associated with deficiency of
Correct Answer: Dihydropyrimidine dehydrogenase
Description: b-hydroxybutyric aciduria, a pyrimidine catabolism disorder due to total or paial deficiency of the enzyme dihydropyrimidine dehydrogenase. This disorder can develop toxicity to 5-fluorouracil, also a substrate for this dehydrogenase enzyme. Reference: Harpers illustrated biochemistry 30th edition
Category:
Biochemistry
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