In a case of hypertensive uveitis, most useful drug to reduce intraocular pressure is –
Correct Answer: Dipivefrine
Description: Glaucoma associated with uveitis is one of the most difficult complications to address and manage.
Medical therapy with topical or systemic antiglaucoma medications is the first step in the treatment of glaucoma-associated uveitis P-blockers, carbonic anhydrase inhibitors (acetamezolanzide), and dipivefrine.
β-blockers are the drug of choice.
Among antiglaucoma medications, prostaglandin analogues (e.g. latanoprost) should not be used as they breakdown the blood aqueous barrier and may exacerbate cystoid macular edema.
When medical therapy with topical or systemic antiglaucoma drugs does not control the IOT and optic nerve or field damage is documented, a surgical procedure becomes mandatory:- laser iridotomy (preferred) or surgical iridectomy.
However, surgery should be performed in a quiet eye under high doses of corticosteroids.
Coming to the question
Amongst the given options, latanoprost and dipivefrin are antiglaucoma drugs (reduce IOT).
However, latanoprost is contraindicated in uveitis glaucoma.
"Pilocarpine and latanoprost are contraindicated as uveitis may be exacerbated". - Parson's
"Latanoprost should be used with caution in patients with a history of intraocular inflammation (iritis/uveitis) and should generally not be used in patients with active intraocular inflammation". -Ciplodac.com
So, in this question the best answer is dipivefrin.
Category:
Ophthalmology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now