All of the statements about exenatide are true except:
Correct Answer: It can be used for treatment of Type 1 diabetes mellitus
Description: Exenatide (Exendin 4) is a GLP-1 receptor agonist that is more resistant to DPP-4 action and cleared by the kidney.
When this drug is given to patients with type 2 diabetes by subcutaneous injection twice daily, it lowers blood glucose and HbA1c levels. It is not indicated in type 1 diabetes.
Exenatide appears to have the same effects as GLP-1 on glucagon suppression and gastric emptying.
Only drugs approved for treatment of type 1 diabetes are insulin and pramlintide.
Category:
Pharmacology
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