Infection with HIV is associated with atrophy in all of the following pas of the brain except –
Correct Answer: Anterior cingulate gyms
Description: Ans. is 'a' i.e., Anterior cingulate gyrus HIV -1 associated neuronopathy is characterized by The infiltration of macrophages into the CNS. The formation of microglial nodule and multinucleated giant cell which result possibly from virus induced fusion of microglia and/macrophages in central white or gray matter Astrocyte activation and damage, neuronal loss paicularly in Hippocampus Basal ganglia Caudate nucleus. o In addition a variable degree of white matter pathology with evidence of broad range of myelin damage ranging from pallor to widespread breakdown and loss leading to accumulation of lipid macrophages in extreme cases with axonal damage in the latter cases, and the presence of HIV-1 in the cerebrospinal spinal ,fluid (CSF) has been repoed..
Category:
Pathology
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