All of the following are decreased in nephrotic syndrome, except –
Correct Answer: Serum fibrinogen
Description: Fibrinogen level is increased in nephrotic syndrome d/t increased hepatic synthesis of fibrinogen.
The largest proportion of protein lost in urine is albumin.
Sometimes, globulins can also be excreted → Immunoglobulin excretion increases the susceptibility of infection.
Other proteins which are decreased -
Transferrin → Microcytic hypochromic anemia
Cholecalciferol binding protein → hypocalcaemia
Thyroxine-binding globulin → Decreased thyroxin level
Antithrombin III → Hypercoagulability
Ceruloplasmin
Category:
Pediatrics
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