All of the following drugs can be used in hypeensive emergency –
Correct Answer: I. V. hydralazine
Description: Usual Intravenous Doses of Antihypeensive Agents Used in Hypeensive Emergencies * Nitroprusside Initial 0.3 (mg/kg)/min; usual 2-4 (mg/kg)/min;maximum 10 (mg/kg)/min for 10 min * Nicardipine Initial 5 mg/h; titrate by 2.5 mg/h at 5-15 min intervals; max 15 mg/h * Labetalol 2 mg/min up to 300 mg or 20 mg over 2 min, then 40-80 mg at 10-min intervals up to 300 mg total * Enalaprilat Usual 0.625-1.25 mg over 5 min every 6-8 h; maximum 5 mg/dose * Esmolol Initial 80-500 mg/kg over 1 min, then 50-300 (mg/kg)/min * Phentolamine 5-15 mg bolus * Nitroglycerin Initial 5 mg/min, then titrate by 5 mg/min at 3-5-min intervals; if no response is seen at 20 mg/min, incremental increases of 10-20 mg/min may be used * Hydralazine 10-50 mg at 30-min intervals ref:Harrison&;s principles of internal medicine,ed 18,pg no 2058
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