A 60 year old female patient complains of diarrhoea and abdominal pain. She was on antibiotic therapy earlier which comprised of Clindamycin. She is a diabetic and is on oral hypoglycemic. Stool culture revealed gram positive motile rods. The colonoscopy is done of this patient and the typical structure is revealed. Which of the following microbe is responsible for this?
Correct Answer: Clostridium difficile
Description: Enteroinvasive E. coli (EIEC) produce a disease very similar to shigellosis. The disease occurs most commonly in children in developing countries and in travelers to these countries. Similar to Shigella, EIEC strains are nonlactose or late lactose fermenters and are nonmotile. EIEC produce disease by invading intestinal mucosal epithelial cells.
Enteroaggregative E. coli (EAEC) causes acute and chronic diarrhea (>14 days in duration) in persons in developing countries. These organisms also are the cause of foodborne illnesses in industrialized countries and have been associated with traveler’s diarrhea and persistent diarrhea in patients with HIV. They are characterized by their specific patterns of adherence to human cells.
Shiga toxin-producing E. coli (STEC) are named for the cytotoxic toxins they produce. STEC has been associated with mild non-bloody diarrhea, hemorrhagic colitis, a severe form of diarrhea, and with hemolytic uremic syndrome, a disease resulting in acute renal failure, microangiopathic hemolytic anemia, and thrombocytopenia.
C. difficile can be isolated from stool culture in 30% of patients with antibiotic-associated diarrhoea and over 90% of those with pseudomembranous colitis, but also from 5% of healthy adults and up to 20% of elderly patients in residential care. The rectal appearances at sigmoidoscopy may be characteristic, with erythema, white plaques or an adherent pseudomembrane or may resemble ulcerative colitis.
Category:
Microbiology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now