Carvedilol is an effective antihypeensive agent that, like propranolol, is capable of blocking beta receptors. An impoant difference between the two drugs is that carvedilol

Correct Answer: has a1 receptor blocking actions
Description: a + b ADRENERGIC BLOCKERS Includes Labetalol, Carvedilol. Carvedilol:- It is a b1 + b2 + a1 adrenoceptor blocker; produces vasodilatation due to a1 blockade as well as calcium channel blockade, and has antioxidant propey. It has been used in hypeension and is the b blocker especially employed as cardioprotective in CHF. Oral bioavailability of carvedilol is 30%. It is primarily metabolized and has a t 1/2 of 6-8 hrs. Ref:- kd tripathi; pg num:-151
Category: Pharmacology
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