A newborn baby presented with profuse bleeding from umbilical stump after bih. Probable diagnosis is _______
Correct Answer: Factor XIII deficiency
Description: major cause of profuse umbilical stump bleeding in newborn is factor Xlll deficiency. The bleeding diathesis in inherited factor XIII (FXIII) deficiency is severe in most patients. Bleeding from the stump of the umbilical cord within the first days to weeks of life is a characteristic sign that occurs in 80% of affected individuals; bleeding from this specific site is uncommon in other inherited hemostatic diseases except afibrinogenemia Reference : Ghai essential of pediatrics, eighth edition, p.no: 349
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Pediatrics
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