A patient ingested some unknown substance and presented with myoclonic jerks, seizures, tachycardia and hypotension. ECG shows a heart rate of 120/min. The arterial blood revealed a pH of 7.25, pCO2 of 30 mm Hg and bicarbonate ions are 15 mmol/L. The most likely poisonous agent is:
Correct Answer: Imipramine
Description: Ans. (C) Imipramine(Ref: KDT 8/e p486, 487)Features are typical of tricyclic antidepressant poisoning. TCAs possess anticholinergic activity that can result in tachycardia. These agents can lead to metabolic acidosis (pH < 7 4, HCO3- < 24 mmol/L). Seizures and myoclonic jerks are other features of TCA poisoning.
Category:
Pharmacology
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now