Nucleoside reverse transcriptase inhibiting drug, which is a guanosine analogue: March 2012

Correct Answer: Abacavir
Description: Ans: C i.e. Abacavir Anti-viral drugs and mechanism of action Ritonavir is a potent retroviral protease inhibitor Zidovudine is a thymidine analogue, the prototype of nucleoside reverse transcriptase inhibitors (NI) Abacavir, a guanosine analogue (nucleoside reverse transcriptase inhibitors), is a potent ARV drug that acts after intracellular conversion to carbovir triphosphate. Acyclovir is a deoxiguanosine analogue antiviral drug (anti-herpes), which requires a virus specific enzyme for conversion to the active metabolite that inhibits DNA synthesis and viral replication
Category: Pharmacology
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