In tumor lysis syndrome following electrolyte abnormalities are seen:
Correct Answer: Hyperuricemia, Hyperphosphatemia, Hyperkalemia
Description: Tumor Lysis Syndrome:Tumor with very high rate of growth- during chemotherapy there will be rapid destruction of the cells that will lead to Tumor Lysis Syndrome. It releases: K+-Hyperkalemia PO42-Hyperphosphatemia Hypocalcemia:Ca2+sequestration by PO42. Hyperuricemia:Nucleic Acid Break down. | can lead to AKI Can prevent/ Tx with aggressive hydration, alopurinol and rasburicase. Common tumors associated with Tumor lysis syndrome - ALL, Burkitt's Lymphoma.
Category:
Pathology
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