Kreb’s cycle and urea cycle are linked by-
Correct Answer: Fumarate
Description: Ans. is 'd' i.e., Fumarate * Fumarate is released during urea cycle, which is an intermediate of Kreb's cycle, thus linking the two.Points to remember about urea cycle1. Urea cycle happens is a pathway active only in liver.2. It is partly mitochondrial, partly cytoplasmic.3. CPS I is the rate limiting enzyme of urea cycle and CPSI is stimulated by NAG (N Acetyl Glutamate) (Please note CPS II is an enzyme of pyrimidine synthesis).4. Net ATP used for detoxifying 1 molecule of ammonia is 1.55. N1 donor of urea is ammonia and N2 donor is aspartate.6. Arginase is the step where in urea is released.
Category:
Biochemistry
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