A 9 year old boy presented to the casualty with high fever, pruritic erythematous rash, joint pain and lymph node enlargement. There is a history of upper respiratory tract infection for which he was on cefaclor – 7 days completed of a 10 day course. The most likely diagnosis is?
Correct Answer: Serum sickness like illness
Description: Serum sickness like reaction can occur following the use of ceain drugs, especially cefaclor in children. It presents with an uicarial / purpuric rash, ahritis, lymphadenopathy and fever. But unlike true serum sickness (type III hypersensitivity response), it is not caused by circulating immune complexes.
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