Which of the following serum value is not in or of a diagnosis of PCOS?
Correct Answer: Reduced serum fasting insulin level
Description: The polycystic ovarian disease is a heterogeneous, multisystem endocrinopathy in women of reproductive age.Endocrinological changes are as follows:1. Oestrone/E2 level rises.2. LH level is raised over 10 IU/mL. FSH level remains normal, but FSH/LH ratio falls.3. SHBG level falls due to hyperandrogenism.4. Testosterone and epi-androstenedione levels rise.5. Fasting blood glucose/fasting insulin, 4.5 suggests insulin resistance.6. Triglyceride level >150 mg/dL-hyperlipidaemia HDL < 50 mg/dL. Testosterone > 2 ng/mL, free T > 2.2 pg/mL (Normal level 0.2-0.8 ng/mL). Normal androstenedione level is 1.3-1.5 ng/mL. DHEA > 700 ng/mL suggests an adrenal tumor.7. Prolactin is mildly raised in 15% cases.8. Fasting insulin is more than 10 mIU/L in PCOS in 50-70/cases.9. Thyroid function tests may be abnormal (hypothyroidism).10. 17-a-hydroxyprogesterone in the follicular phase > 300 ng/dL suggests adrenal hyperplasia due to 21-hydroxylase deficiency.11. Urinary coisol < 50 mg/24 h.Ref: Shaw&;s textbook of gynecology; 16th edition; Page no: 432
Category:
Gynaecology & Obstetrics
Get More
Subject Mock Tests
Practice with over 200,000 questions from various medical subjects and improve your knowledge.
Attempt a mock test nowMock Exam
Take an exam with 100 random questions selected from all subjects to test your knowledge.
Coming SoonGet More
Subject Mock Tests
Try practicing mock tests with over 200,000 questions from various medical subjects.
Attempt a mock test now